Ohio State Route 260 is a highly curvy route to the Ohio River, in southeasternmost Ohio. It begins in eastern Noble County, along Ohio Route 78 east of Caldwell. It runs southerly and southeasterly from there, twisting and turning through hilly, forested backcountry for 34 miles. Much of it is in the Wayne National Forest. As it meets Ohio Route 26 in the tiny hamlet of Bloomfield, it turns easterly toward New Matamoras, where it ends at Ohio Route 7 along the Ohio River.