US Route 501 is a north-south route from Myrtle Beach to Durham and the middle of Virginia.  The southern end in Myrtle Beach is at US Route 17, the route that catches all nearby US Routes before they fling themselves into the Atlantic Ocean. US Route 501 runs north from there to Laurinburg, North Carolina, where it is joined by US Route 15.  US Route 15 and US Route 501 continue northward together all the way to Durham.  In Durham, US Route 501 reasserts its independence and heads north into Virginia, crossing US Route 58 at South Boston.  Next, US Route 501 proceeds to Lynchburg.  Around this area, US Route 501 gets more mountainous.  It winds its way through some of the Virginia mountains to Buena Vista, where US Route 501 ends at US Route 60.

My current photo of US Route 501 replaces an older featured photo of the route. Though the new featured photo appears next, the older photo is still viewable, at the bottom of this page.

I replaced an older photo of US Route 501 with this newer photo taken in Conway, South Carolina. This newer photo shows a scene on the west side of town, along the main alignment of US Route 501 through town. This intersection is where US Route 378 begins its journey cutting west across the middle of South Carolina. US Route 701 is concurrent with US Route 501 here; a block south of here, US Route 701 splits from US Route 501 to head to Georgetown instead of Myrtle Beach (the ultimate goal of US Route 501's journey south from here). This photo was taken on a trip to Myrtle Beach in June 2024. My older photo of US Route 501, below, precedes this photo by only two months.

My formerly-featured photo of US Route 501 shows the northbound trailblazer for those leaving the interchange with US Route 64's freeway bypass around Pittsboro, North Carolina.  US Route 64's main alignment through the Pittsboro area is a freeway bypass around the north side of town. A diamond interchange connects to US Route 501, which runs concurrently with US Route 15 on a north-south surface road.  The signage depicted reassures drivers leaving the interchange toward the north.  This photo was taken during my trip across the Delmarva and the Carolinas in April, 2024.
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