Iowa Route 333 is a route far in the extreme southwestern corner of Iowa, connecting Interstate 29 to the town of Hamburg. Like many of the former Iowa routes numbered in the 300's, Iowa Route 333 is a tiny connector; however, unlike most of the routes in the 300's, Iowa Route 333 survived the decimation of nearly every route numbered in that range. Iowa Route 333 is only about a mile and a half long, and its western end is the interchange with Interstate 29 marked as "Exit 1". From that interchange, Iowa Route 333 heads east along North Street, which ironically runs into the south side of Hamburg. Iowa Route 333 turns northerly on Washington Street, and ends at a junction where US Route 275 comes from the east and continues north on Washington Street. That junction, at Washington and "E" Street, is central to the town of Hamburg.