US Route 422 runs in two separate sections in Ohio and Pennsylvania; the two sections are separated by an unsigned concurrency with US Route 22 and US Route 322.  The western end is the Cleveland Public Square, in downtown Cleveland Ohio, which also hosts US Route 6, US Route 20, and the northeastern end of US Route 42.  US Route 422 heads east-southeasterly from there through northeastern Ohio and New Castle, Pennsylvania, to join US Route 22 at Ebensburg, Pennsylvania.  US Route 422 isn't signed from here to Harrisburg, and it also isn't signed along US Route 322 from Harrisburg to Hershey.  But at Hershey, it appears to be reborn heading east from US Route 322, on another road.  US Route 422's eastern section runs through Reading, where it becomes a 4-lane highway with occasional interchanges.  It stays a 4-lane highway through Pottstown, until US Route 422's penultimate endpoint in King of Prussia, Pennsylvania, at US Route 202.  This final interchange is right next to US Route 202's interchange with Interstate 76.

My photo for US Route 422 depicts a route marker on Interstate 80's eastbound offramp to the US highway, at an interchange in Girard, Ohio.  This is just northwest of Youngstown, Ohio.  I took this photo during an early part of my trip to the Northeastern United States in October 2014.

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