Interstate 70 cuts east-west across Indiana's middle, linking Terre Haute, Indianapolis, and Richmond. Interstate 70 enters Indiana from Illinois just west of Terre Haute, heading east-northeast from St. Louis toward Indianapolis.  In central Indiana, Interstate 70 reaches Indianapolis, becoming one of the two highways that are still allowed to penetrate to the core of the city.  From Indianapolis, Interstate 70 continues nearly due east to Richmond, Indiana, and Columbus, Ohio.  The border crossing into Ohio happens on the eastern edge of Richmond itself.

The exit list for Interstate 70 begins in the west and continues east, to coincide with the national mile numbering scheme.

Interstate 70 enters Indiana just west of Terre Haute, concurrent with US Route 40...
Exit 1 is only accessible from the west, and it used to be the place where US Route 40 split away from Interstate 70. Now, US Route 40 hangs onto Interstate 70 for a longer distance, and this exit heads to National Avenue, West Terre Haute, and Terre Haute proper...
Exit 3 is to Darwin Road, linking to West Terre Haute...
Exit 7 is the exit to the main north-south highway through the Terre Haute area: US Route 41, with US Route 150 along for the ride. Evansville is included with Terre Haute as a control city...
Exit 11A leads to Indiana Route 641, which begins and heads south to flank Terre Haute to the southeast...
Exit 11B leads to the northern continuation of the road carrying Indiana Route 641, which picks up the eastern continuation of US Route 40 as that route splits from Interstate 70...
Exit 23 is for Indiana Route 59, with access to Linton and Brazil...
Exit 37 is for Indiana Route 243, a route that leads to Putnamville...
Exit 41 is for US Route 231, connecting to Cloverdale and Greencastle...
Exit 51 is for a local road called County Road 1100 W (Indiana Route 42 is a block to the south)...
Exit 59 is a diverging diamond for Indiana Route 39, providing a link to Monrovia and Belleville:
Exit 66 is for Indiana Route 267, which allows access to Plainfield and Mooresville...
Exit 68, at Interstate 70's foray into Indianapolis, is for Ameriplex Parkway and Ronald Reagan Parkway, with access to Indianapolis Airport...
Exit 73A leads to Interstate 465 south and Interstate 74 east, toward Cincinnati...
Exit 73B leads to Interstate 465 north and Interstate 74 west, toward Peoria...
Exit 75 is an access that allows travelers to access Sam Jones Parkway, as long as they're going from eastbound to eastbound or westbound to westbound...
Exit 77 is for Holt Road...
Exit 78 is for Harding Street...
Exit 79A is for West Street...
Exit 79B is for Illinois Street and Meridian Street...
Exit 80 accesses Interstate 65 south toward Louisville, as Interstate 70 joins Interstate 65 north through downtown Indianapolis...
Exit 83A from Interstate 70 accesses a bunch of surface streets in downtown Indianapolis...
Exit 83B accesses Interstate 65 north toward Chicago, as Interstate 70 splits from Interstate 65...
Exit 85A is for Rural Street southbound:
Exit 85B is for Keystone Avenue northbound, along the same alignment as Rural Street (westbound sees a single exit 85 for these two street designations):
Exit 87 is for Emerson Avenue:
Exit 89 is a fountain interchange to Shadeland Avenue...
Exit 90, nearly intertwined with exit 89, leads to Interstate 465...
Exit 91 leads to Post Road as Interstate 70 begins leaving the Indianapolis area:
Exit 96 accesses Mount Comfort Road, at a partial cloverleaf interchange with directional onramps:
Exit 104 is for Indiana Route 9, with access to Maxwell and Greenfield:
Exit 115 is a half-folded diamond to Indiana Route 109, which links to Wilkinson and Knightstown:
Exit 123 is a fountain interchange for Indiana Route 3, which provides access to New Castle and Spiceland...
Exit 131 is a common diamond interchange to Wilbur Wright Road:
Exit 137 is for Indiana Route 1, which provides a connection to Connersville and Hagerstown:
Exit 145 provides access to Centerville:
Exit 149A is the first half of a directional interchange, with this first ramp reaching Williamsburg Pike and Tom Raper Way (this once was designated US Route 35 into Richmond):
Exit 149B is the other half of the interchange, leading to US Route 35 northbound.  Southbound US Route 35 joins Interstate 70 east here (the space on the sign used to mention Indiana Route 38, which ends just to the north):
Exit 151 is a single-point interchange to US Route 27 and Chester Blvd.:
Exit 153 is a fountain interchange to Indiana Route 227 in Richmond, and Union City is listed a a control city:
Exit 156A is the first half of an interchange right on the Ohio border, and this first ramp leads to US Route 40 east, also known as National Road...
Exit 156B is the part of the interchange leading to US Route 40 east toward Lewisburg, Ohio...
The interchange with exits 156A and 156B are right is the Ohio border, and Interstate 70 continues east toward Dayton and Columbus in Ohio, carrying US Route 35 with it for the moment.  Eventually, Interstate 70 gets all the way to Baltimore, Maryland!

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