^Looking north near the junction with Iowa 220 in the Amana Colonies area, May 2022.
US Route 151 is a northeast-southwest highway through Iowa and Wisconsin, but in Iowa, it runs from the Amana area through Cedar Rapids to Dubuque. The southern end, actually, is a bit south of Amana, at Interstate 80. This endpoint is a rural diamond interchange west of Iowa City. From there, US Route 151 gets started by passing through the Amana colonies and bending northeasterly into the Cedar Rapids area. A business alignment of US Route 151 heads through the heart of Cedar Rapids, but the main alignment has been rerouted as a bypass around the southern and eastern sides of the city. The eastbound part of the bypass, along the south side, follows the US Route 30 freeway, and the northbound portion around the east side of town follows Iowa Route 13. Then, at Marion, US Route 151 converges into a single route and leaves the area toward the northeast. US Route 151 passes through Anamosa, Monticello, and Cascade, before joining US Route 61 north into Dubuque. US Routes 151 and 61 stay together to cross the Mississippi River out of Dubuque into the very southwestern corner of Wisconsin.
My photo of US Route 151 signage comes from its interaction with US Route 6, very near its southern end. US Route 151 has a short jog to the east along US Route 6 as it's trying to make its way northward. This photo was taken at the west end of that jog along US Route 6; the signage depicted faces east for westbound travelers reaching the conclusion of the concurrency. This photo was taken in February 2016 as I was making my way to Omaha down Interstate 80, which is just to the south of this photo's place of origin.
Here are some more photos taken along US Route 151 in Iowa:
Guide marker for US Route 151, along with US Route 20 and US Route 51, on a city street in Dubuque.
US Route 151's exit to the west end of Iowa 64 in Anamosa.
US Route 151's exit to the north end of Iowa 1, near Anamosa. This is just southwest of the exit to Iowa 64.
Looking north at the point where Iowa 13 splits from US Route 151, on the east side of Marion.
Northbound guide signage in the Amana Colonies, at the intersection of US Route 151 and Iowa 220.
As US Route 151 is almost at its southern end, its southward progression is interrupted by a short westward jog along US Route 6. These signs show westbound travelers the western extent of the concurrency shared between the two routes. According to these signs, US Route 151 turns south here toward its southern terminus.
This photo looks north at the junction with the westward ramps, found at the interchange with Interstate 80 that marks US Route 151's southern end.
Looking south at US Route 151's interaction with the westbound ramps at Interstate 80.
A closeup shot of the southern end marker for US Route 151.