In Indiana, US Route 36 runs east-west, spanning the middle of the state. The point at which it crosses the Illinois border into Indiana is about midway between the points where Interstate 70 and Interstate 74 do that. It runs almost perfectly due east to Indianapolis, thence wrapping around the south side of town via Interstate 465. In the eastern half of Indiana, US Route 36 parts from the Indianapolis area deviating a bit northeasterly, but straightening out at Pendleton to once head nearly due-east to the Ohio border. (US Route 40 and Interstate 70 take over as the routes heading due east out of Indianapolis.) The Ohio border crossing is north of Richmond and Interstate 70, and US Route 36 continues east into its final state, toward Greenville, Ohio.