US Route 16 runs from Rapid City, South Dakota, west to the eastern entrance into Yellowstone National Park, in northwestern Wyoming.  The eastern end is at Interstate 90, at a point where US Route 16 starts out moving south along an eastern bypass around Rapid City.  US Route 16 heads immediately west for the Black Hills, serving as a scenic route through Custer and beyond into the state of Wyoming.  Once it reaches Wyoming, US Route 16 passes through Newcastle, and then joins Interstate 90 west at Moorcroft.  In Gillette, US Route 16 and US Route 14 both divert northwesterly, away from Interstate 90.  US Route 16 eventually splits from US Route 14 to cross Buffalo, Wyoming and reach Worland.  At Worland, US Route 16 joins US Route 20, and both routes turn westerly at Greybull, where they also include US Route 14.  US Routes 16, 14, and 20 all run west together through Cody to the eastern entrance of Yellowstone National Park. US Route 14 and US Route 16 both end at this gate to the park, while US Route 20 continues farther west.

My photo for US Route 16 comes from a set of guide markers posted at an intersection with US Route 85 in Newcastle, Wyoming. Northbound travelers see this signage posted at the intersection. I had an older photo here on this page, with a caption that read, "I hope to get a better picture of US Route 16 in the future." I got a better photo in July 2026, and it's the one you see here!

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