Indiana State Route 352 is an east-west route mainly in southern Benton County, in west-central Indiana. Indiana Route 352 splits from US Route 52 west of Lafayette, to run through Oxford and Boswell. Just before hitting the Illinois state line, it joins Indiana Route 71 south through Ambia to end concurrently with Indiana Route 71 at a point on the state line, where Indiana Route 26 becomes Illinois Route 9.