Indiana State Route 67 is one of Indiana's big diagonal routes, starting in Vincennes and running northeast past the Indianapolis area to enter the state of Ohio. Indiana Route 67 starts at US Route 41 and US Route 150 duplexed just north of Vincennes and US Route 50, and then it connects to Spencer, Martinsville, and I-465 around Indianapolis. Indiana Route 67 isn't signed on Interstate 465 around Indianapolis, but it splits from Interstate 465 to Pendleton, Muncie, Portland, and the Ohio state line, where it becomes Ohio State Route 29.