Interstate 55 begins in Chicago along Lake Shore Drive (US Route 41) and heads southwest along the former route of US Route 66, crossing the Mississippi River into St. Louis, Missouri. It passes along Joliet's western flank and connects to Normal, Bloomington, and Springfield before it reaches the St. Louis metroplex.
Exit 94 from the Interstate 55/72 concurrency reaches Stevenson Drive in Springfield:
Exit 96A is the first of two ramps at a cloverleaf to Illinois 29; this first ramp accesses Illinois 29 south toward Taylorville:
Exit 96B meets Illinois 29 north and South Grand Avenue:
Exit 98A is the eastern continuation of Interstate 72, which runs with US Route 36 toward Decatur:
Exit 98B is a cloverleaf ramp to the eastern beginning of Illinois 97, which runs along Clear Lake Avenue:
Exit 100A is part of yet another cloverleaf, and it leads to Illinois 54 toward Clinton:
Exit 100B is the second half of a cloverleaf, leading to Sangamon Avenue:
Exit 105 is the northern end of Business Loop 55, which leads to Sherman as well as Springfield:
Exit 109 is for Illinois 123, leading to Williamsville and Petersburg:
Exit 115 provides access to Elkhart, and Logan County Highway 10:
Exit 119 connects Interstate 55 to Broadwell, and Logan County Highway 22:
Exit 123 spawns a new Business Loop 55 that heads northeast into Lincoln, Illinois:
Exit 126 is a fountain interchange to Illinois 10 and the western end of Illinois 121, providing access to Lincoln and Mason City:
Exit 127 is a terminal stack interchange at the southern end of Interstate 155, which connects with Peoria:
Exit 133 provides access to the northern end of Lincoln's iteration of Business Loop 55:
Exit 140 is for Atlanta, Illinois, and for Lawndale, Illinois:
Exit 145 leads to US Route 136, McLean, and Heyworth:
Exit 154 is for Shirley, connecting to McLean County Highway 34:
Exit 157A is part of an interchange where Interstate 74 and US Route 51 join Interstate 55 north around the west side of Bloomington-Normal; this first exit accesses Interstate 74 east and US Route 51 south (toward Indianapolis or Decatur)...
Exit 157B provides access to the southern beginning of Business Loop 55 through Bloomington...