Indiana State Route 110 is two unrelated east-west segments of highway in northern Indiana, and I really don't understand why one of them can't be renumbered as another three-digit number ending in "10". The first segment is only two and a half miles south of DeMotte, connecting Indiana Route 10 to US Route 231. The second and longer section of Indiana State Route 110 starts at Indiana Route 17 south of Culver and runs east toward Mentone, ending as a merger with an east-west section of Indiana Route 25.