Ohio State Route 206 is a short north-south route through the hills of northwestern Coshocton County, with the northern end of the highway barely protruding into Holmes County. The southern end of Ohio Route 206 is at Ohio Route 541 in a rural spot west of Coshocton. Ohio Route 206 runs north from there to pass through Newcastle and Walhonding. The northern reaches of Ohio Route 206 cross the county line into Holmes County, and the route soon ends at US Route 62.