Ohio State Route 217 is a short east-west route found in Lawrence County, in Ohio's southernmost lobe. About seven miles after heading east out of Ohio Route 141, it reaches a fork where Ohio Route 141 bears left, toward the northeast. If a traveler reaching this fork bears right instead, they will reach the western beginning of Ohio Route 217. Ohio Route 217 winds through the hilly countryside of southernmost Ohio, mainly staying in rural areas. Ohio Route 217 reaches its final destination of Miller, Ohio, when it ends at Ohio Route 7.