Ohio State Route 128 is a route running from Hamilton toward the southwest corner of Ohio. It starts by poking westward from US Route 127, to cross the Great Miami River. Once it reaches the west side of the river, Ohio Route 128 turns south to follow the western bank of the Great Miami River. It follows the river downstream, all the way until it reaches Hooven, in the southwestern corner of Ohio (across the river from Cleves). Ohio Route 128 ends in Hooven, at US Route 50. This is only a couple of miles north of the Ohio River.