^Looking north from exit 297 to Clifton, October 2023.
Interstate 57 runs from the City of Chicago south-southwesterly through Champaign and Effingham to the central backbone of southern Illinois, leaving the state near its southern tip into Missouri (NOT Kentucky). Out of Interstate 57's 380 miles, 358 are spent in Illinois, and this mileage total is higher than that of any other Interstate's mileage in Illinois. Interstate 57 serves as somewhat of an alternate to Interstate 55 between Chicago and Memphis; as Interstate 55 bows west to connect to St. Louis and come back southeast, Interstate 57 serves as a more direct alternative for long-term travelers.
Exit 220 is another interchange with US Route 45, as Interstate 57 crosses over it near Pesotum:
Exit 229 meets Champaign County Highway 18, connecting to Savoy and Monticello:
Exit 232 is for Curtis Road, providing access to Savoy:
Exit 235A is the first half of a cloverleaf interchange marking the eastern end of Interstate 72, but this first ramp leads to University Avenue in Champaign:
Exit 235B leads to the eastern start to Interstate 72:
Exit 237A is the first half of the interchange with Interstate 74, and this ramp leads to Interstate 74 east toward Indianapolis; the southbound offramp to Interstate 74 east is being rebuilt as a flyover (as of 2023):
Exit 237 provides access to Interstate 74 west, toward Peoria:
Exit 238 is to Olympian Drive in Champaign:
Exit 240 is to Market Street on the far northern end of Champaign: