US Route 319 runs from Wadley, in east-central, Georgia, to Apalachicola, Florida, on the Gulf Coast of the Florida panhandle. The route runs mainly in a southwestern direction, that's a bit more southerly than westerly. The northern end is at US Route 1 and Georgia Highway 78 in Wadley, Georgia, to be specific. US Route 319 passes through towns in Georgia like Dublin, Fitzgerald, Tifton, and Thomasville, plus Tallahassee in Florida. US Route 319, for its last hurrah, joins US Route 98 west at a point south of Tallahassee, so it can end at US Route 98's bridge over the Apalachicola River into Apalachicola. That's where the southern end marker for US Route 319 is posted, anyway.