^Westbound trailblazer at the eastern terminus, heading away from US Route 67 near Littleton, February 2018.
Illinois Route 101 is an east-west route south of the Macomb area, in a very rural section of western Illinois. It exists in northern Schuyler County and southeastern Hancock County.
The western end of Illinois 101 is at Illinois 61 in Augusta, the largest town entered by Illinois 101 at about 600 people:
Near Brooklyn, Illinois, Illinois 101 meets the northern end of Illinois 99...
Near the aptly-named town of Littleton, Illinois 101 ends at US Route 67: